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GLOBAL NEWSLETTER
JANUARY 2019

IN THIS ISSUE

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IeDEA Asia-Pacific’s January think tank in Bangkok, Thailand, on expanding cohort research to address treatment challenges among young adults living with HIV 


Welcome
IeDEA is starting off 2019 with exciting research and plans for the coming year.  We have 20 regional and multiregional abstracts that will be presented at CROI Seattle in early March, and more that will be presented at IWHOD Athens in late March.  There are a series of IeDEA Working Group and global meetings that will be held in association with CROI where we will strategize over new research directions, and consider how to better support early-stage investigators and develop grant applications that leverage IeDEA as a global research platform.  

IeDEA consensus statement
IeDEA’s potential to impact policy and practice is reflected in our first ever IeDEA consensus statement: Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa.  The article was published this month in the Journal of the International AIDS Society and is complemented by our recent supplement highlighting these research priorities in the Journal of Virus Eradication.
IeDEA Asia-Pacific welcomes new Scientia PhD students to the Kirby Institute

The regional data center of IeDEA Asia-Pacific is at the Kirby Institute, University of New South Wales, Sydney, Australia.  Under the leadership of co-PI Professor Matthew Law, their team has been awarded two of the 9, university-wide 2019 Scientia PhD positions for early-stage investigators (below), who were selected on the basis of applications nested within IeDEA Asia-Pacific.  The purpose of the scholarship program is to train researchers whose work will “improve the lives of people in local and global communities.”  


Dr. Win Min Han is a Burmese clinical trials physician at HIV-NAT, Thailand, one of IeDEA Asia-Pacific’s adult HIV cohort sites.  










Mr. Malede Mequanent Sisay is a lecturer in Biostatistics and Epidemiology at the University of Gondar in Ethiopia.  






Both will contribute to IeDEA Asia-Pacific’s regional research activities, studying HIV treatment outcomes in children and adults.
Early-Stage Investigator Profiles

Julie Jesson, IeDEA West Africa
Julie Jesson, MSc, PhD, is an epidemiologist working for Inserm U1027, at the University of Toulouse 3, France.  Her research interests are focused on growth and nutritional care for children and adolescents living with HIV in Africa.  During her PhD, she studied malnutrition among children on antiretroviral therapy enrolled in the IeDEA pediatric West African Database (pWADA).  She is assessing nutritional interventions in this population through the WADANUT study.  She pursued her post-doctoral research within the IeDEA multiregional consortium, in close partnership with the IeDEA Southern Africa team at the University of Cape Town, evaluating stunting and growth among adolescents living with HIV.  Dr. Jesson has been part of the IeDEA Pediatric Working Group since 2016 and is working within the IAS CIPHER cohort consortium to assess global patterns of growth and immune system development among adolescents living with HIV. 



Gabriela Patten, IeDEA Southern Africa
Ms. Patten holds a Masters in Epidemiology degree from the London School of Hygiene and Tropical Medicine and has worked as a field epidemiologist for Médecins Sans Frontières (MSF).  She is currently based at the University of Cape Town, South Africa, where she is pursuing her PhD.  Her doctoral work is focused on exploring the difficult to treat and hard to reach populations in the HIV epidemic, specifically those with advanced HIV disease and children with treatment failure.  Her work involves describing how these populations and their outcomes have changed as ART programs have matured in Southern Africa in the context of evolving guidelines and treatment options.  Her research aims to inform treatment strategies to improve the outcomes of these hard to reach populations.  She is currently helping to lead a multiregional IeDEA concept studying outcomes of children and adolescents treated with raltegravir.
Recent Publications 

Contributions of traditional and HIV-related risk factors on non-AIDS-defining cancer, myocardial infarction, and end-stage liver and renal diseases in adults with HIV in the USA and Canada: a collaboration of cohort studies. The Lancet HIV. 2019 Jan 22. 

Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA). J Int AIDS Soc. 2019 Jan;22(1):e25218.

Cardiovascular disease-related mortality and factors associated with cardiovascular events in the TREAT Asia HIV Observational Database (TAHOD). HIV Med. 2019 Jan 8. 

Trends in mortality among ART-treated HIV-infected adults in the Asia-Pacific region between 1999 and 2017: results from the TREAT Asia HIV Observational Database (TAHOD) and Australian HIV Observational Database (AHOD) of IeDEA Asia-Pacific. J Int AIDS Soc. 2019 Jan;22(1):e25219. 

Mortality and losses to follow-up among adolescents living with HIV in the IeDEA global cohort collaboration. J Int AIDS Soc. 2018 Dec;21(12):e25215.

Global temporal changes in the proportion of children with advanced disease at the start of combination antiretroviral therapy in an era of changing criteria for treatment initiation. J Int AIDS Soc. 2018 Nov;21(11):e25200. 

Aging with HIV: what effect on mortality and loss to follow-up in the course of antiretroviral therapy? The IeDEA West Africa Cohort Collaboration. HIV AIDS (Auckl). 2018 Nov 16;10:239-252. 


For updated lists of regional publications, please go to our website at https://www.iedea.org/publications/.


Grant-Writing Resources


The Anatomy of an [NIH] Specific Aims Page from the BioScience Writers website http://www.biosciencewriters.com/NIH-Grant-Applications-The-Anatomy-of-a-Specific-Aims-Page.aspx

NIH YouTube tutorial on navigating NIH peer review for fellowship grants https://www.youtube.com/watch?v=_Gr-D68NawQ&t=17s

 

Funding Opportunities
The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

If you have any questions, comments, or concerns related to the content of this newsletter, please contact Aimee Freeman- afreeman@jhu.edu.

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