ICTS Digest | February 2018
What's new with the ICTS? Check out the latest information on our website: icts.wustl.edu
Translational Science Success Stories
Eric Lenze, MD, Psychiatry, has moved findings from multiple JIT projects and funding through a 2015 CTRFP Funding Program Pilot award to direct multicenter clinical trials assisted by the NCATS Trial Innovation Network.
Studies are designed to improve cognition, depression and rehabilitation in older adults using behavioral and pharmacologic interventions. READ MORE>>
Congratulations to Brian Gage, MD, MSc, who recently released results of the Genetic InFormatics Trial. Published in JAMA, the randomized trial studied clinical outcomes using genotype-guided warfarin dosing in 1,650 older patients undergoing elective hip or knee surgery. 
The work, supported in part by the ICTS, was described by NIH Director Francis Collins as “an encouraging success story for the emerging field of pharmacogenomics” in the NIH Director's Blog.
ICTS Highlights

The Hope Center Cores may now be used through the Just-In-Time (JIT) Core Usage Funding Program. The monthly call for JIT applications supports the use of eligible ICTS Cores to obtain final data for an extramural grant submission or data leading to a concrete improvement in patient care at BJH or SLCH.

The ICTS Liaison Program was launched in November 2017. 90+ faculty members representing WU and all ICTS partner institutions have agreed to serve as ICTS Liaisons. The Liaisons will share ICTS opportunities with colleagues in their Schools, Departments, and Divisions and their feedback will inform ICTS initiatives. If you are interested in serving as an ICTS liaison, contact us at icts@wustl.edu. 
The first annual ICTS symposium was held on January 16, 2018. This year’s theme was “Advancing Precision Medicine through Translational Genomics” and the Keynote Speaker was Eric Green, MD, PhD, Director of NHGRI. This talk was followed by breakout sessions, poster presentations, and an ICTS core fair. 
It was a success with over 250 people in attendance, 70+ posters, and very positive reviews!  We are now soliciting ideas for next year, please send them to icts@wustl.edu.

Congratulations to Clinical Research Training Center alumni, Dr. Ana Maria Arbelaez and Dr. Peter Nagele, featured in the NCATS January Translational Research Highlight!  Learn how this ICTS-supported program fosters the next generation of translational scientists by supporting the development of key skills, knowledge, and acquisition of core competencies to build independent careers.

The Center for Clinical Studies (CCS), in partnership with the Institute for Clinical and Translational Sciences (ICTS), is launching a new Multicenter Clinical Trial Support Service that will provide specialized expertise and trial implementation support to faculty who seek to conduct investigator-initiated multicenter clinical trials. In addition to providing focused guidance on study organization, sponsor interactions, efficient start-up, and patient recruitment, this unit will offer full clinical trial coordinating center services and help to execute trials in partnership with Department-based study teams and investigators. Faculty will also be connected with the resources of the national Trial Innovation Network to optimally support the success of their studies.
To lead this effort, Suresh Vedantham, MD, Professor of Radiology & Surgery, has been appointed Assistant Dean for Clinical Research in the School of Medicine, and Medical Director of the Center for Clinical Studies.

Michelle Jenkerson, RN, BS, RRT, CCRC has been newly appointed as the Center for Clinical Studies Associate Director.  She will work closely with Yi Zhang, RN, JD (Assistant Dean for Clinical Research, CCS Administrative Director), Suresh Vedantham, MD (Assistant Dean for Clinical Research in the School of Medicine, Medical Director of the CCS), and ICTS leadership in her role.
ICTS, in collaboration with Venture Café, is hosting "Precision Medicine: From the Lab to Life-hacks" for the month of February!  Every Thursday will feature a different aspect of precision medicine's future impact and contributions to personal health. READ MORE>>
The Center for Clinical and Research Ethics will host the 2018 Daniel Bisno Ethics in Medicine Lecture on Friday, March 9, 2018, from 12pm-1pm in the McDonnell Science Building, Cori Auditorium. Gloria Wilder, MD, MPH, (CEO, Core Health & VP, Innovation and Preventive Health, Centene Corporation) will present “The Business of Social Transformation: Driving value in the American Healthcare System.” Lunch will be provided; RSVP is required by visiting the above link.
Funding Opportunities
As a Clinical and Translational Science Award Hub, we are eligible for limited competitions including U01, R21, U24, and other grant mechanisms. See the NCATS website for a full listing of Funding Opportunities

PAR-15-172: Collaborative Innovation Award, Clinical and Translational Science Award (CTSA) Program (U01); due March 8, 2018.

Modifications for PAR-18-244:  "Collaborative Innovation Award, Clinical and Translational Science Award (CTSA) Program (U01 Clinical Trial Optional)".  Notice: NOT-TR-18-013.

PAR-18-245: Limited Competition: Exploratory CTSA Collaborative Innovation Awards; due March 29, 2018.

PAR-16-343: Exploratory CTSA Collaborative Innovation Awards (R21); due March 29, 2018.

The deadline to apply to the NIH Clinical NIH Clinical and Translational Research Course for Ph.D. Students is March 30, 2018.
Research Education and Training
*  The Clinical Research Training Center (CRTC) is accepting Advanced Training in Clinical Investigation applications for the MTPCI and MSCI programs through April 17, 2018.

*  The Office of Training Grants will host the next NIH Mock Study Section on April 27, 2018. READ MORE>>

* In an effort to promote excellence and professional development for clinical research professionals, the new Accelerating Clinical Coordinator Excellence (ACCE) Programs are now available. READ MORE>>

*  The Office of Training Grants, with support from ICTS, developed the WUSTL Grants Library, a resource designed to help investigators at all career stages. The library houses over 150 awarded grants as well as stock language, proposal templates, and tools.  Anyone with a WUSTL key can access the library via Box: https://wustl.box.com/v/wustlgrantslibrary.  Please contact Betsy Abente at: eabente@wustl.edu if you wish to share your awarded grant or have difficulties accessing the site.

* Advanced Summer Program for Investigation and Research Education (ASPIRE) applications are due February 20, 2018; Program dates are June 1, 2018 - July 31, 2018.
ICTS Partners
* SLU's Keith S. Naunheim, MD, was elected president of The Society of Thoracic Surgeons. READ MORE>>

* Peter Tonellato, PhD, joined the MU School of Medicine as director of the newly created Center for Biomedical Informatics Research.

* Gene therapy for Duchenne muscular dystrophy advances toward clinical trials.

* New Blood Pressure Guidelines Highlight Need for Lifestyle Changes. READ MORE>>
Upcoming WU Events
>15: Precision Medicine: From the Lab to Life-hacks
>20: Skandalaris Center: Breakfast & Panel Discussion
>20: Research Forum: Child Health
>22: Precision Medicine: From the Lab to Life-hacks
>22: Epidemiology and Clinical Outcomes Research Seminar Series

>1: Research Forum - Medical Health Sciences
>9: Daniel Bisno Ethics in Medicine Lecture
>19: Master of Population Health Sciences (MPHS) Program
>20: Research Forum - Child Health
>22: Epidemiology and Clinical Outcomes Research Seminar Series

>4: WUNDIR Meeting
>5: Research Forum - Medical Health Sciences
>17: Research Forum - Child Health
>25: 8th Annual PCOR Symposium
HRPO SWAT! hours will be held on Fridays from 9:30am-1:00pm in the Mid Campus Center (MCC), 2nd Floor, Room 2042.
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Our address is:
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Phone: (314) 362-9829

*Cite the NIH CTSA Grant Number UL1TR002345 when your research was supported by ICTS/CTSA funds or services*